Is Z Nation coming back?

No — Z Nation ended on December 28, 2018, after its fifth season on Syfy.

Z Nation was a science-fiction horror series that aired from 2014 to 2018. The show was set three years after a zombie virus outbreak had devastated the United States, and it followed a group of survivors as they attempted to transport the only known survivor of the plague from New York to California, where a viral lab awaited his blood. The storyline focused on their journey across a post-apocalyptic America, facing various threats while the survivor's mysterious condition and the dark secret he carried posed ongoing risks.

The series featured a cast including Russell Hodgkinson as Steven "Doc" Beck, Kellita Smith as Roberta Warren, Keith Allan as Alvin Bernard Murphy, Anastasia Baranova as Addison "Addy" Carver, DJ Qualls as Citizen Z, Nat Zang as 10K, Pisay Pao as Cassandra, and Ramona Young as Kaya. It held a rating of 7.2 on TVMaze and each episode had a runtime of about 61 minutes. The show’s combination of action, horror, and science-fiction elements contributed to its distinctive post-apocalyptic narrative.