When does Superman & Lois return?

Tyler Hoechlin and Elizabeth Tulloch star as the title characters Clark Kent / Superman and Lois Lane, respectively. Jordan Elsass and Alex Garfin portray the couple's twin sons Jonathan and Jordan Kent, with Michael Bishop replacing the former in the third season. The series was intended to be part of the Arrowverse's Earth-Prime in its first season, but as the series went on, following the cancellation of planned crossovers with Supergirl and Batwoman due to the COVID-19 pandemic, showrunner Todd Helbing and Warner Bros. decided to keep the show separate.
In the first season, Clark Kent / Superman and Lois Lane return to Smallville with their sons Jonathan and Jordan, where they are reacquainted with Lana Lang, her husband Kyle Cushing, and their daughter Sarah. During the second season, Superman's painful visions lead him to an encounter with Bizarro. The third season has Superman contending with the plots of Intergang as Lois Lane suffers from Stage 3 inflammatory breast cancer.