The series premiered on May 27, 2021, on Paramount+; it is the second Nickelodeon-based series created for the streaming service. The surviving voice actors of the titular "Rugrats" reprise their roles from the original series. The adult roles of the adult roles have been recast, including Betty DeVille who was originally voiced by the returning Kath Soucie. The series has a vast array of secondary and tertiary characters.
Just like the Rugrats focuses on the experiences of a courageous, adventurous one-year-old baby named Tommy Pickles.