When does One Tree Hill return?

One Tree Hill premiered on September 23, 2003, on The WB and UPN. The show is set in the fictional town of Tree Hill, North Carolina. The main storyline in the early seasons is the relationship between two half-brothers, Lucas and Nathan Scott, who start out as enemies but bond as the show progresses. The opening credits were originally accompanied by the song "I Don't Want to Be" by Gavin DeGraw.