The series aired near-simultaneously in Japan on TV Tokyo and its affiliates and in the United States on Adult Swim's Toonami programming block (along with an Adult Swim Canada simulcast) from April to June 2025. In the utopian year 2049, the world-renowned neuroscientist Dr. Skinner has discovered a miracle analgesic drug known as "Hapna" that completely relieves the user of any pain, shortly before disappearing off the face of the Earth. A task force of five agents, called "Lazarus", is assembled to locate Skinner within 30 days and get him to divulge a vaccine before the first wave of Hapna users die.