In the utopian year 2049, the world-renowned neuroscientist Dr. Skinner has discovered a miracle analgesic drug known as "Hapna" that completely relieves the user of any pain. Three years later in October 2052, Skinner resurfaces to the public in an online video to announce the drug has a three-year half-life and that soon, everyone who took it will die. A task force of five agents, called "Lazarus", is assembled to locate Skinner within 30 days and get him to divulge a vaccine before the first wave of Hapna users die.