Interview with the Vampire centers on the life story of vampire Louis de Pointe du Lac, as told to veteran journalist Daniel Molloy, to whom he previously gave an unpublished interview in 1973. The series is the first series set in the Immortal Universe, a shared universe based on Anne Rice's novels. The first two seasons cover the events of the novel The Vampire Lestat.
Interview with the Vampire centers on the life story of vampire Louis de Pointe du Lac. Louis is romanced and later made a vampire by the charismatic Lestat de Lioncourt. Daniel Molloy previously gave an unpublished interview in 1973.