The series revolves around three friends named Ed, Edd (nicknamed Double D), and Eddy. They live in a suburban cul-de-sac in the fictional town of Peach Creek along with fellow neighbourhood children Kevin, Nazz, Sarah, Jimmy, Rolf, Jonny, and the Kanker Sisters, Lee, Marie and May. The trio frequently invents schemes to make money from their peers to purchase their favourite confection, jawbreakers.
Ed, Edd n Eddy follows the lives of "the Eds", three boys who all share nicknames of the name Edward, but differ greatly in their personalities. The three devise plans to obtain money from the other kids in their cul-de-sac to buy jawbreakers. The series took place mostly within the fictional town of Peach Creek, and new locations were rarely introduced.