Cow and Chicken is the third of Cartoon Network's Cartoon Cartoons. The series follows the adventures of two talking animal siblings. The original pilot appeared as an episode of the animation showcase series What a Cartoon!. The popularity of the original short allowed Hanna-Barbera to give it the green light for a full series.
The series focuses on the misadventures of two unlikely yet somehow biological siblings. The two are often caught in escapades with their flamboyant enemy, the Red Guy. The series draws on eccentric, surreal, grotesque, and repulsive humor.