The show originally aired from August 21, 2004, to August 25, 2006. It follows the lives of Brandy and Mr. Whiskers, a pampered dog and a hyperactive rabbit. The show was created by sitcom writer Russell Marcus for the Disney Channel. Thirty-nine episodes were produced.
A pampered dog (Brandy) and an easily excited rabbit (Mr. Whiskers) face a new life of challenges together when they fall out of an airplane and become stranded in the Amazon rainforest. Stories follow the titular duo as they attempt to adapt to their new surroundings.