When does B Positive return?

The multicamera series premiered on CBS on November 5, 2020 as a Thursday-night entry in the 2020–21 television season. The series was renewed for a second season, which premiered on October 14, 2021. In May 2022, the series was canceled after two seasons.
The series initially follows Drew, a therapist and newly divorced father with B-positive blood who needs a kidney donor. The sitcom is inspired by the true story of series creator Marco Pennette, who received a kidney transplant in 2013.