The series ran from April 12, 2003, to August 17, 2008, for a total of five seasons. It featured much of the surviving cast from the original series reprising their roles. The series explores the daily lives of Tommy Pickles, his little brother Dil and his childhood friends, now tweens/adolescents.
Ten years after the events of Rugrats, Tommy, Dil, Chuckie, Kimi, Angelica, and Susie are now tweens/teens. Episodes often involve the cast dealing with common issues of preteens and teenagers.