The series is based on the 1961 Disney animated feature of the same name and its 1996 live-action remake. The show focuses primarily on three puppies: Lucky, Rolly, Cadpig, and Spot, a chicken who wants to be a dog and a member of the Bark Brigade. Other puppies appearing in the show included the fearless, three-legged Tripod, the friendly dimwitted Dipstick, the constantly urinating Wizzer, the fashion-conscious diva Two-Tone, and the Sheepdog mix, Mooch.
Unlike the original film, the series is set in England in the 1990s, on the Dearly Farm. The show focuses primarily on three puppies: Lucky, Rolly, his cheerful, laid-back, and always-hungry brother; and Cadpig, their uncanny but loveable sister who is the runt of the family.