Hugh Laurie

as Richard Roper

as Dr. Gregory House

as Eric Peterson

as Neville

as Ryan Clark

as Felix Carmichael

as The Prince Regent

as Lieutenant The Honourable George Colthurst St. Bartleigh

as Control

as Major de Coverley

as Etienne LeBlanc

as Dr James Nicholson

as Peter Laurence

as Hiller B. Zobel

as Control

as Dr. Eldon Chance

as Bertram Wilberforce "Bertie" Wooster

as Leo Hopkins

as Director

as Various Characters

as Paul Slippery

as Various

as Mr. Wolf

as Narrator